Blood disorder

Our patients range in age from infants to young adults and come from every corner of Virginia and North Carolina. Unique Needs, Personal Care At CHKD, we believe that children with cancer and blood disorders deserve personal care that addresses their unique emotional, spiritual and educational needs as well as their medical ones. A dedicated and highly trained team w ill help you and your family coordinate the care your child needs and provide a safe and supportive environment before, after and during treatment. Outpatient Care The Cancer and Blood Disorders Center, located on the second floor of the hospital, offers outpatient medical treatment in a comfortable setting.

Blood disorder

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Hemophilia is a rare, inherited bleeding disorder that can range from mild to severe, depending on how much clotting factor is present in the blood. Hemophilia results from a genetic defect found on the X chromosome. Women have two X chromosomes. Women who have one X chromosome with the defective Blood disorder are termed carriers and they can pass the disease onto their sons.

Due to random chromosome activation, some women carriers may range from asymptomatic to symptomatic depending on how much of their factor VIII or IX is inactivated.

Men have one X and one Y chromosome, so if their X chromosome has the defective gene, they will have hemophilia. Because blood does not clot properly without enough clotting factor, any cut or injury carries the risk of excessive bleeding.

In addition, people with hemophilia may suffer from internal bleeding that can damage joints, organs, and tissues over time. In the past, people with hemophilia were treated with transfusions of factor VIII obtained from donor blood, but by the early s these products were discovered to be transmitting blood-borne viruses, including hepatitis and HIV.

Von Willebrand disease is an inherited condition that results when the blood lacks functioning von Willebrand factor, a protein that helps the blood to clot and also carries another clotting protein, factor VIII.

It is usually milder than hemophilia and can affect both males and females.

Blood disorder

Women are especially affected by von WIllebrand disease during menses. Von Willebrand disease is classified into three different types Types 1, 2, and 3based on the levels of von Willebrand factor and factor VIII activity in the blood.

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Type 1 is the mildest and most common form; Type 3 is the most severe and least common form. With early diagnosis, people with von Willebrand disease can lead normal, active lives. People with mild cases may not require treatment, but should avoid taking drugs that could aggravate bleeding, such as aspirin and ibuprofen, without first consulting with a doctor.

More serious cases may be treated with drugs that increase the level of von Willebrand factor in the blood or with infusions of blood factor concentrates.

It is important for people with von Willebrand disease to consult with their doctors before having surgery, having dental work, or giving birth, so that proper precautions can be taken to prevent excessive bleeding. You may be referred to a hematologist, a doctor who specializes in the treatment of blood disorders.

If you find that you are interested in learning more about blood diseases and disorders, here are a few other resources that may be of some help:Celgene Corp.

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Blood conditions information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.

The Children's Cancer and Blood Disorders Center at CHKD is eastern Virginia's top referral center for pediatric cancer and blood disorders, treating infants to young adults.

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